Christopher Benner Selected Research

9 alpha,11 alpha,15 alpha- trihydroxy- 16- phenoxy- 17,18,19,20- tetranorprosta- 4,5,13- trienoic acid (TPT)

1/2021	TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation.
12/2020	Topoisomerase 1 inhibition therapy protects against SARS-CoV-2-induced inflammation and death in animal models.

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Christopher Benner Research Topics

Disease

8	Infections 01/2021 - 01/2018
6	COVID-19 01/2021 - 04/2020
6	Neoplasms (Cancer) 01/2019 - 01/2017
4	Inflammation (Inflammations) 01/2021 - 07/2010
3	Breast Neoplasms (Breast Cancer) 01/2018 - 08/2010
2	Virus Diseases (Viral Diseases) 01/2021 - 09/2020
2	Heart Diseases (Heart Disease) 01/2014 - 08/2013
1	Coccidioidomycosis 02/2022
1	Disease Progression 02/2022
1	Drug Overdose 01/2022
1	Substance-Related Disorders (Drug Abuse) 01/2022
1	Colitis 01/2020
1	Ulcerative Colitis 01/2020
1	Pulmonary Embolism 01/2020
1	Venous Thrombosis (Deep-Vein Thrombosis) 01/2020
1	Hypertriglyceridemia 01/2019
1	T-Cell Lymphoma (Lymphoma, T Cell) 01/2019
1	Carcinogenesis 01/2019
1	Genomic Instability 01/2018
1	Zika Virus Infection 01/2018
1	Human Influenza (Influenza) 01/2018
1	Fibrosis (Cirrhosis) 11/2017
1	Non-alcoholic Fatty Liver Disease 11/2017
1	Hepatocellular Carcinoma (Hepatoma) 11/2017
1	Colorectal Neoplasms (Colorectal Cancer) 10/2017
1	Fever (Fevers) 01/2017
1	Hypoxia (Hypoxemia) 09/2015
1	Prostatic Neoplasms (Prostate Cancer) 01/2015
1	Genetic Translocation (Chromosomal Translocation) 12/2014
1	Hypoglycemia (Reactive Hypoglycemia) 07/2014
1	Neurodegenerative Diseases (Neurodegenerative Disease) 04/2014
1	Neuroinflammatory Diseases 04/2014
1	Huntington Disease (Huntington's Disease) 04/2014
1	Atherosclerosis 07/2010
1	Endotoxemia 07/2010

Drug/Important Bio-Agent (IBA)

4	Proteins (Proteins, Gene)FDA Link 01/2020 - 10/2017
3	RNA (Ribonucleic Acid)IBA 02/2022 - 01/2017
3	DNA (Deoxyribonucleic Acid)IBA 01/2019 - 09/2015
3	ChromatinIBA 01/2018 - 08/2010
2	Transcription Factors (Transcription Factor)IBA 02/2022 - 08/2010
2	InterferonsIBA 01/2021 - 09/2020
2	9 alpha,11 alpha,15 alpha- trihydroxy- 16- phenoxy- 17,18,19,20- tetranorprosta- 4,5,13- trienoic acid (TPT)IBA 01/2021 - 12/2020
2	Topotecan (Hycamtin)FDA LinkGeneric 01/2021 - 12/2020
2	Viral RNAIBA 01/2021 - 09/2020
2	Antiviral Agents (Antivirals)IBA 12/2020 - 04/2020
2	Pharmaceutical PreparationsIBA 04/2020 - 01/2020
2	HeterochromatinIBA 01/2019 - 01/2018
1	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 01/2022
1	Opioid Analgesics (Opioids)IBA 01/2022
1	RNA-Binding Proteins (RNA-Binding Protein)IBA 01/2021
1	Nucleic AcidsIBA 09/2020
1	Carrier Proteins (Binding Protein)IBA 09/2020
1	VaccinesIBA 04/2020
1	AnticoagulantsIBA 01/2020
1	Dextrans (Dextran)FDA Link 01/2020
1	Heparin Lyase (heparin lyase)IBA 01/2020
1	Heparitin Sulfate (Heparan Sulfate)IBA 01/2020
1	Phenobarbital (Luminal)FDA Link 01/2020
1	sodium sulfate (sodium bisulfate)FDA LinkGeneric 01/2020
1	HLA-DR Antigens (HLA-DR)IBA 01/2019
1	Lipoproteins (Lipoprotein)IBA 01/2019
1	NucleotidesIBA 01/2019
1	Triglycerides (Triacylglycerol)IBA 01/2019
1	Satellite RNA (Satellite RNAs)IBA 01/2018
1	RNA Polymerase II (RNA Polymerase B)IBA 01/2018
1	Immunoglobulin A (IgA)IBA 11/2017
1	B7-H1 AntigenIBA 11/2017
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 11/2017
1	AntigensIBA 11/2017
1	Interleukin-10 (Interleukin 10)IBA 11/2017
1	Histones (Histone)IBA 10/2017
1	Enhancer RNAsIBA 01/2017
1	Anesthetics (Anesthetic Agents)IBA 01/2017
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2017
1	5-hydroxymethylcytosineIBA 09/2015
1	EnzymesIBA 09/2015
1	5-Methylcytosine (5 Methylcytosine)IBA 09/2015
1	Co-Repressor ProteinsIBA 01/2015
1	Cytidine DeaminaseIBA 12/2014
1	Hormones (Hormone)IBA 07/2014
1	Glucose (Dextrose)FDA LinkGeneric 07/2014
1	Glucagon (Glukagon)FDA Link 07/2014
1	Insulin (Novolin)FDA Link 07/2014
1	CytokinesIBA 04/2014
1	polyglutamineIBA 04/2014
1	Huntingtin ProteinIBA 04/2014
1	oxidized low density lipoproteinIBA 07/2010
1	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 07/2010
1	LipopolysaccharidesIBA 07/2010
1	NF-kappa B (NF-kB)IBA 07/2010

Therapy/Procedure

8	Therapeutics 01/2021 - 08/2013
1	Resuscitation 01/2017